Syro XP software controls the instrument functions and calculates all amounts and volumes of amino acids and reagents required. Each cycle of the synthesis can receive a completely different protocol. This flexibility allows not only single or multiple couplings, but also complete freedom in the choice of coupling strategies within any synthesis cycle.
Pre-activation of the amino acids can be performed for all the synthesis cycles or just for individual ones. The amino acids can be activated in parallel or individually directly prior to their distribution.
The Tip Synthesis option is designed for applications that require large numbers of peptides in small quantities (1–5 μmol). Each Tip Synthesis Module can be used to synthesize up to 96 peptides at a time. Each peptide is synthesized in a 0.4 ml tip with PE frit where accurate dispensing of reagents is essential. The Syro I system can accommodate 1 Tip Synthesis Module, and the Syro II system can accommodate 3–6 modules, allowing up to 576 peptides to be made at the same time.
Syro I is equipped with one type-U reactor block that can accept 2, 5 and 10 ml reactors. An infinitely variable vortexer guarantees an optimal mixing of the reactants.
Digital injection pumps enable dosing with microliter precision and user-friendly software allows all technical possibilities of the robot to be easily implemented.
The modular construction offers great flexibility with respect to the number and size of the storage and reaction containers. Optionally, all storage containers for reagents and reactors can be equipped with the capability to work under inert gas.